Drug use typology, demographic covariates, and associations with condomless anal sex: A latent class analysis among a U.S. national cohort of men who have sex with men

•Latent Class Analysis indicated six patterns of substance use.•Substance use patterns ranged from “no use” to “diverse use”.•Patterns of substance use among MSM may differ by demographic characteristics.•Membership in two classes was associated with more condomless anal sex partners.