Elevated retinal cGMP is not associated with elevated circulating cGMP levels in a canine model of retinitis pigmentosa.

Laurence M Occelli,Kelian Sun,Paige A Winkler, Brandy J Morgan, Simon M Petersen-Jones

PloS one（2022）

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摘要

cGMP levels in the plasma from PDE6A-/- was not elevated when compared to control dogs. At the 2-month timepoint, cGMP plasma levels would not be a useful biomarker for disease.

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关键词

elevated retinal cgmp,retinitis pigmentosa,cgmp levels

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