Genome-wide association study of osteonecrosis of the jaw in Danish patients receiving antiresorptive therapy for osteoporosis: A case-control study

Alma B. Pedersen,Sven E. Nørholt,Lars Rejnmark,Bente Langdahl,Thomas Starch-Jensen,Henrik T. Sørensen

Bone Reports（2022）

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摘要

•This is a large GWAS study, including 40 ONJ cases and 124 controls.•We did not detect any significant genome-wide associations.•Of the 43 SNPs which previously have been associated with ONJ, none were replicated in our study.

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关键词

Antiresorptive treatment,Bisphosphonates,Case control,Genes,Osteonecrosis of the jaw,Pharmacogenomics,Single nucleotide polymorphism

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