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A new diterpenoid from Salvia santolinifolia boiss

Zahra Sargazifar, Marziyeh Esmaeilzadeh Kashi, Zahra Tazik, Javad Mottaghipisheh, Seyed Hamzeh Hosseini, Hermann Stuppner, Abolfazl Shakeri, Javad Asili

NATURAL PRODUCT RESEARCH(2024)

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摘要
Phytochemical study of the Salvia santolinifolia root extract resulted in the isolation of one new quinone diterpenoid, aegyptinone E (1) as well as two known ones, aegyptinone A (2) and aegyptinone D (3). All the isolated compounds were reported for the first time from S. santolinifolia. Spectroscopic analyses including 1 D and 2 D NMR and HRESIMS were used to determine the chemical structures. Aegyptinone A (2) showed moderate antibacterial activity against Staphylococcus aureus, Staphylococcus epidermis, and Bacillus subtilis with MIC of 25 mu g/mL.
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关键词
Quinone diterpenoids,Salvia,antibacterial activity,Lamiaceae
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