Association of Endovascular Thrombectomy vs Medical Management With Functional and Safety Outcomes in Patients Treated Beyond 24 Hours of Last Known Well: The SELECT Late Study.

Amrou Sarraj,Timothy J Kleinig,Ameer E Hassan,Pere Cardona Portela,Santiago Ortega-Gutierrez,Michael G Abraham,Nathan W Manning,James E Siegler,Nitin Goyal,Laith Maali,Spiros Blackburn,Teddy Y Wu,Jordi Blasco, Arturu Renú,Navdeep S Sangha,Juan F Arenillas,Margy E McCullough-Hicks,Adam Wallace,Daniel Gibson,Deep K Pujara,Faris Shaker,Mercedes de Lera Alfonso,Marta Olivé-Gadea,Mudassir Farooqui,Juan S Vivanco Suarez, Zachary Iezzi,Jane Khalife,Colleen G Lechtenberg, Syed K Qadri, Rami B Moussa,Mohammad A Abdulrazzak,Tareq S Almaghrabi,Osman Mir,James Beharry,Balaji Krishnaiah,Megan Miller, Najwa Khalil,Gagan J Sharma,Aristeidis H Katsanos,Ali Fadhil,Kelsey R Duncan,Yin Hu,Sheryl B Martin-Schild,Georgios K Tsivgoulis,Dennis Cordato,Anthony Furlan,Leonid Churilov,Peter J Mitchell,Adam S Arthur, Mark W Parsons,James C Grotta,Clark W Sitton,Marc Ribo,Gregory W Albers,Bruce C V Campbell

JAMA neurology（2023）

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摘要

In this study of treatment beyond 24 hours of last known well, EVT was associated with higher odds of functional independence compared with medical management, with consistent results obtained in PS-matched subpopulations and patients with presence of mismatch, despite increased odds of sICH. Our findings support EVT feasibility in selected patients beyond 24 hours. Prospective studies are warranted for confirmation.

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endovascular thrombectomy

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