Challenges in next generation sequencing of homology recombination repair genomic variants in prostate cancer: A nationwide survey and calibration project in China

Huanwen Wu,Liqun Zhou,Xiaoyan Zhou,Qiang Wei,Nengtai Ouyang,Jianyong Shao,Jian Huang,Zhiyong Liang

Prostate International（2022）

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摘要

The discrepancies observed in our survey and EQA test affect the authenticity of HRR gene test results for prostate cancer, underlining the need to establish guidelines for HRR gene testing and variant interpretation in China, and to optimize HRR gene testing in clinical practice to improve management and patient care.

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关键词

prostate cancer,homologous recombination repair gene testing,next-generation sequencing,national questionnaire survey,external quality assessment

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