Bioenergetic Crisis in ICU-Acquired Weakness Gene Signatures Was Associated With Sepsis-Related Mortality: A Brief Report.

Seibi Kobara,Milad G Rad,Jocelyn R Grunwell,Craig M Coopersmith,Rishikesan Kamaleswaran

Critical care explorations（2022）

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摘要

Our findings demonstrated a biological association between sepsis-related mortality and ICUAW signatures in the early phase of sepsis. Defects in energy metabolism and muscle fiber formation were associated with sepsis-related mortality.

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关键词

immunosuppression, and catabolism syndrome,intensive care unit-acquired weakness,mortality,persistent inflammation,post-intensive care syndrome,sepsis

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