Clinical and Radiological Findings and Treatment of 8 Cases of Superficial Siderosis at Our Hospital

Background : Superficial siderosis (SS) is an intractable disease characterized by hemosiderin deposition in the subpial layers of the brain, typically the brainstem, cerebellum, and spinal cord. Patients with SS usually exhibit slow cerebellar ataxia and sensorineural hearing disturbances. It was recently reported that spinal magnetic resonance imaging (MRI) revealed an epidural cerebrospinal fluid (CSF) leak with spinal dural defects in patients with SS. However, there is currently no effective treatment that can improve the symptoms of SS. These characteristic findings are sometimes observed in patients with spontaneous intracranial hypotension (SIH).