Behavioral analysis of mice overexpressing PP5 specifically in the mice CA3 region of hippocampus.

Proceedings for Annual Meeting of The Japanese Pharmacological Society(2022)

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摘要
[Purpose] We have explored the possibility that protein phosphatase 5 (PP5), together with PP1 and PP2A, promotes desensitization of GABAB receptors and attenuates receptor action by dephosphorylating the 892nd serine residue of mouse GABAB receptors. In this study, we investigated the possibility that dephosphorylation of GABAB receptors in the hippocampal CA3 region affects the behavior of mice.
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关键词
pp5,hippocampus,mice ca3 region
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