Relationship between circadian rhythm disorder and nocturia

Since the discovery of clock genes and the identification of circadian oscillating factors around them, the concept of circadian rhythms surrounding us has changed dramatically. Clinical studies and basic research clock genes have revealed the mechanisms by which various factors cause circadian rhythm disorder due to abnormalities in clock genes. Jet lag, stress, and aging can also affect clock gene function, and the resulting circadian rhythm disorder can cause various diseases. Bladder function is also regulated by clock genes, and circadian rhythm disorders cause lower urinary tract disease such as nocturia. In this workshop, I will talk about clock genes and the circadian bladder function in mice, nocturia caused by abnormal clock genes, and its clinical applications.