EP331/#950 Phyllodes tumor: epidemiological characteristics in patients over 40 years old

Objectives

We aim to determine the clinical, histological, therapeutic, and prognostic characteristics of phyllodes tumors in patients over 40.

Methods

This is a retrospective study conducted at the department of gynecology at Farhat Hached Teaching Hospital Sousse Tunisia over a 5-year period (2017 to 2021) recruiting all the female patients with histologically proven phyllodes tumors of the breast diagnosed at an age over 40.

Results

The average age of occurrence was 51 years [41–63] and 45,4% of the patients were menopausal. The revelation was clinical, with the self-discovery of a breast lump in 90.9%. The mean tumor size was 75 mm [36–144]. All patients had breast surgery. The conservative treatment was decided in 27,2% of cases. Adjuvant radiotherapy was performed on 4 women (36.3%) of patients.Chemotherapy was indicated for a patient with pulmonary and bone metastases. The 3-year follow-up was very favorable in 81.8% with a local recurrence in 2 patients.

Conclusions

In women over 40, Phyllodes tumors are bulky tumors that may often result in a mastectomy. The treatment is mainly surgical. The evolution may be marked by local recurrence and rarely metastases.