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EPO has multiple positive effects on astrocytes in an experimental model of ischemia

Jonas Blixt,Yutong Song,Michael Wanecek,Eli Gunnarson

Brain Research（2022）

Cited 1|Views2
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Abstract
•EPO increases glutamate uptake in astrocytes undergoing ischemia.•EPO preserves Na,K-ATPase function in ischemic astrocytes.•EPO restores intracellular pH in astrocytes via an effect on NHE.•EPO have beneficial effects on energy production in astrocytes and neurons.
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Key words
Erythropoietin,Astrocyte,Neuroprotection,Glutamate,Ischemia
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