Safety and Tolerability of an Antimalarial Herbal Remedy in Healthy Volunteers: An Open-Label, Single-Arm, Dose-Escalation Study on Maytenus senegalensis in Tanzania.

Kamaka Kassimu,Florence Milando,Justin Omolo, Abel Mdemu,Gloria Nyaulingo,Hussein Mbarak,Latipha Mohamed,Ramla Rashid,Saumu Ahmed,Mohammed Rashid, Hania Msami, David Damiano,Beatus Simon,Thabit Mbaga,Fatuma Issa,Omar Lweno,Neema Balige, Omary Hassan,Bakari Mwalimu,Ali Hamad,Ally Olotu,Andreas Mårtensson,Francis Machumi,Said Jongo,Billy Ngasala,Salim Abdulla

Tropical medicine and infectious disease（2022）

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摘要

was demonstrated to be safe and tolerable when administered at a dose of 800 mg every eight hours a day for four days. This study design may be adapted to evaluate other herbal remedies.

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关键词

M. senegalensis,Tanzania,antimalarial,healthy volunteer,herbal remedy,safety,tolerability

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