Chemotherapy-induced hand foot syndrome: comparative efficacy and safety of pharmacological prophylaxis - systematic review and Bayesian network meta-analysis.

Mathan Kumar Ramasubbu, Shampa Maji, Milan Padhan,Rituparna Maiti,Debasish Hota,Saroj Kumar Das Majumdar,Anand Srinivasan

BMJ supportive & palliative care（2022）

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摘要

Only celecoxib (200 mg two times per day) showed significant prevention of the incidence of moderate to severe HFS. Pyridoxine (400 mg once daily) and urea cream (10%) have to be evaluated further in larger randomised trials.

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关键词

Breast,Clinical decisions,Gastrointestinal (lower),Pharmacology,Skin care,Supportive care

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