Oral tolerance and oral immunotherapy for food allergy: Evidence for common mechanisms?

Cellular Immunology（2023）

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摘要

•Oral tolerance (OT) in humans prevents peanut allergy (PA) when given in the first year of life.•OIT for PA leads to tolerance when administered in the first years of life.•OIT and OT in young children expands peanut-specific IgG4.•OIT in older children results in deletion and anergy of peanut-specific Type 2 cells.

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food allergy,oral tolerance,oral immunotherapy

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