Erxian decoction alleviates cisplatin-induced premature ovarian failure in rats by reducing oxidation levels in ovarian granulosa cells.

Jiao Liu,Yang Yang,Yueshuang He,Chenran Feng,Haosong Ou,Jiadi Yang,Yao Chen,Fengming You,Binghao Shao, Jirong Bao, Xingyu Guan, Fangfang Chen,Piwen Zhao

Journal of ethnopharmacology（2022）

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摘要

EXD boosted the ovary's antioxidant and anti-apoptotic capabilities while enhancing the estrous cycle and hormone output. These findings strongly suggested that EXD may contribute to the alleviation of POF and ovarian granulosa cells senescence.

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关键词

POF,EXD,KGN,GCs,ROS,HRT,ELISA,AMH,E2,FSH,LH,DCFH-DA,Ct

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