Type I and Ir pleuropulmonary blastoma (PPB): A report from the International PPB/DICER1 Registry.

Alexander T Nelson,Anne K Harris,Dave Watson,Doug Miniati,Mike Finch,Junne Kamihara,Sarah G Mitchell,David B Wilson,Katie Gettinger,Arun A Rangaswami, José M Campos,Sara Lederman,Brad A Feltis,Lauren M Vasta,Laura A Harney,Douglas R Stewart,Louis P Dehner,Yoav H Messinger,D Ashley Hill,Kris Ann P Schultz

Cancer（2023）

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摘要

For young children with type I PPB, outcomes are favorable, but complete resection is indicated because of the risk for progression. Chemotherapy may be useful in a subset of children at increased risk for recurrence/progression. Efforts to risk stratify children with type I PPB to optimize outcomes while reducing treatment-related side effects are underway.

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关键词

DICER1,DICER1 tumor predisposition,lung cyst,pleuropulmonary blastoma,type I PPB,type Ir PPB

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