Skeletal muscle phenotypic switching in heart failure with preserved ejection fraction.

Eng Leng Saw, Louis Dominic Werner,Payman Zamani,Julio A Chirinos,María Valero-Muñoz,Flora Sam

Frontiers in cardiovascular medicine（2022）

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摘要

The HFpEF model recapitulates the SkM phenotypic switching seen in HFpEF patients. This model is suitable and relevant to study SkM phenotypic switching in HFpEF.

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关键词

atrophy,exercise intolerance,heart failure with preserved ejection fraction,oxidative metabolism fibers,skeletal muscle

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