A novel approach for quantitative electrogram analysis for driver identification: Implications for ablation in persistent atrial fibrillation.

MSE analysis-guided driver ablation in addition to PVI for PsAF could be feasible, efficient, and safe. An RA < LA mMSE gradient before ablation could predict freedom from arrhythmia. The RA-LA MSE gradient could be useful for guiding ablation strategy selection.