NK cells reduce anergic T cell development in early-stage tumors by promoting myeloid cell maturation.

Robin S Lindsay,Marit M Melssen,Katarzyna Stasiak,Jessica L Annis,Amber N Woods,Anthony B Rodriguez,Michael G Brown,Victor H Engelhard

Frontiers in oncology（2022）

引用 0|浏览15

暂无评分

摘要

We conclude that an important function of NK cells is to drive proper APC maturation CD40L during responses to early-stage tumors, reducing development of anergic T cells. The reduced development of anergic T cells resulting in improved tumor control and T cell responses when NK cells were present.

查看译文

关键词

B16 melanoma,CD40L blockade,anergic T cells,antigen presenting cell (APC),natural killer (Nk) cell

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要