Jujuboside B inhibits febrile seizure by modulating AMPA receptor activity.

Baohua Jin,Wanjun Bai,Jiaojiao Zhao,Xia Qin,Han Guo,Yahui Li,Jie Hao,Siruan Chen,Zuxiao Yang,Hui Bai,Zongmao Zhao,Qingzhong Jia, Changzheng Dong,Zhuo Huang,Dezhi Kong,Wei Zhang

Journal of ethnopharmacology（2022）

Cited 1|Views16

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Abstract

JuB suppressed the excitability of hippocampal neurons by inhibiting the activity of AMPAR and reducing the intracellular free calcium, thereby relieving febrile seizures.

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Key words

AMPA receptor,Febrile seizure,Jujuboside B,Neuronal excitability

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