Timing and genotype distribution of symptomatic and asymptomatic sapovirus infections and re-infections in a Nicaraguan birth cohort.

Fredman González,Marta Diez-Valcarce,Yaoska Reyes,Nadja A Vielot,Christian Toval-Ruíz,Lester Gutiérrez,Omar Zepeda,Edwing Centeno Cuadra,Patricia Blandón,Hannah Browne,Natalie M Bowman,Samuel Vílchez,Jan Vinjé,Sylvia Becker-Dreps,Filemón Bucardo

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases（2023）

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摘要

The first sapovirus infections occurred at approximately 11 months of age, whereas the median time to symptomatic re-infection was 7.2 months. Re-infections with the same sapovirus genotype were rare during 2 years of life suggesting genotype-specific protection after natural infection.

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关键词

Birth cohort,Genotype distribution,Natural protection,Re-infection,Sapovirus,Timing of infection

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