Pathogenicity and anti-infection immunity of animal H3N2 and H6N6 subtype influenza virus cross-species infection with tree shrews

Virus Research(2022)

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摘要
•New emerging swine and avian influenza viruses could infect tree shrews and cause mild symptoms without adaptation.•Animal influenza viruses induced effective innate and adaptive immune responses in tree shrews.•Tree shrews may be a suitable mammalian model to study the cross-species transmission of animal influenza A viruses.
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关键词
Tree shrew,Low pathogenic,Cross-species infection,Swine influenza virus,Avian influenza virus,Anti-infection immunity,Transmissibility
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