Integration of metabolomics and transcriptomics to reveal ferroptosis is involved in Tripterygium wilfordii polyglycoside tablet-induced testicular injury.

Zhiyan Qin,Gengyi Zhang,Shiqin Jiang, Fangqing Ning,Zhongxiang Zhao,Min Huang,Jing Jin

Journal of ethnopharmacology（2022）

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摘要

These results suggested that ferroptosis was involved in the testicular damage caused by TWP, which might provide a new strategy to alleviate TWP- induced testicular injury.

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关键词

Ferroptosis,Glutathione,Metabolomics,Testicular injury,Transcriptomics,Tripterygium wilfordii polyglycoside Tablet

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