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Relevance of Molecular Profiling in Patients With Low-Grade Endometrial Cancer.

Stephanie W Vrede,Jenneke Kasius,Johan Bulten,Steven Teerenstra,Jutta Huvila,Eva Colas,Antonio Gil-Moreno,Dorry Boll,Maria Caroline Vos,Anne M van Altena,Jasmin Asberger,Sanne Sweegers,Willem Jan van Weelden,Louis J M van der Putten,Frédéric Amant,Nicole C M Visser,Marc P L M Snijders,Heidi V N Küsters-Vandevelde,Roy Kruitwagen,Xavier Matias-Guiu,Vit Weinberger,Casper Reijnen,Johanna M A Pijnenborg

JAMA network open（2022）

Cited 2|Views16
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Abstract
This cohort study found that patients with low-grade EC had an excellent prognosis independent of molecular subgroup. These findings do not support routine molecular profiling in patients with low-grade EC, and they demonstrate the importance of primary diagnostic tumor grading and selective profiling in low-grade EC to increase cost-effectiveness.
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Key words
molecular profiling,cancer,low-grade
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