Enzymatic cascade reactions for the efficient synthesis of natural products

TETRAHEDRON(2022)

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Abstract
Enzymatic cascade reactions are powerful technologies to develop environmentally friendly and cost-effective synthetic processes to manufacture natural products and other valuable molecules. The application of Single-Enzyme-Catalyzed Cascade reactions (SECC) greatly improves the efficiency of synthesis. This digest focuses on the recent inspiring examples of the application of cascade reactions catalyzed by a single enzyme in synthesizing natural products and natural product-like molecules, with particular emphasis on the unique advantages of these strategies.(c) 2022 Elsevier Ltd. All rights reserved.
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Key words
Chemoenzymatic synthesis, Cascade reactions, Total synthesis, Natural products
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