Two New Antibacterial Isoindolin-1-Ones from the Leaves of Cigar Tobacco
CHEMISTRY OF NATURAL COMPOUNDS(2022)
摘要
Two new isoindolin-1-ones, tobindoles E and F ( 1 and 2 ), were isolated from the leaves of cigar tobacco (a variety of Nicotiana tabacum ). Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their antibacterial activity. The results showed that both compounds exhibited high antibacterial activity against the 11 microbial strains isolated from the oral saliva of smokers.
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关键词
Cigar tobacco,isoindolin-1-ones,antibacterial activity
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