Male Breast Cancer

Purpose of Review Male breast cancer (MBC) accounts fo r less than 1% of all breast cancers. Because of this rarity, treatment data is limited to retrospective analyses. The purpose of this paper is to improve awareness of risk factors and the presentation of MBC and to review current data regarding management. Recent Findings Risk factors for MBC include age, androgen-estrogen imbalance, family history, and genetic predisposition. Palpable mass and nipple changes are the most common manifestation. Delays in diagnosis lead to a higher stage at presentation when compared to women. Most patients have HR-positive disease. Although treatment recommendations for MBC are like female breast cancer, men are more likely to undergo mastectomy and less likely to receive adjuvant therapies. Additional investigation is warranted to determine optimal management strategies for MBC, including participation in randomized clinical trials. Resources such as gender-specific materials and support services are needed to improve the quality of life after diagnosis.