A phenomenological model of proton FLASH oxygen depletion effects depending on tissue vasculature and oxygen supply.

Wei Zou, Haram Kim,Eric S Diffenderfer,David J Carlson,Cameron J Koch,Ying Xiao,BoonKeng K Teo,Michele M Kim,James M Metz,Yi Fan,Amit Maity,Costas Koumenis,Theresa M Busch,Rodney Wiersma,Keith A Cengel,Lei Dong

Frontiers in oncology（2022）

引用 2|浏览24

暂无评分

摘要

We developed 1D, 2D, and 3D oxygen depletion simulation process to obtain the dynamic HRF and derive the proton FEDMF related to the dose delivery parameters and the local tissue vasculature information. The phenomenological model can be used to simulate or predict FLASH effects based on tissue vasculature and oxygen concentration data obtained from other experiments.

查看译文

关键词

FLASH effect,hypoxic reduction factor,oxygen depletion,proton,vasculature

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要