Potential roles of oxidative distress on neurodegeneration in Parkinson's disease with neuropsychiatric symptoms.

Dan-Ning Li,Teng-Hong Lian, Wei-Jiao Zhang,Ya-Nan Zhang,Peng Guo,Hui-Ying Guan,Jing-Hui Li,Ming-Yue He,Wen-Jing Zhang, Wei-Jia Zhang,Dong-Mei Luo,Xiao-Min Wang, Wei Zhang

Frontiers in aging neuroscience（2022）

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摘要

Oxidative distress characterized by the elevations of HO and NO levels may closely correlate with the neurodegeneration in brain regions related to PD-NPSs. Thus, therapeutic antioxidants may become an important target for PD-NPSs therapy.

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关键词

Parkinson's disease,anti-oxidative enzyme,cerebrospinal fluid,free radicals,neuropathological proteins,neuropsychiatric symptoms

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