Chlorthalidone vs. Hydrochlorothiazide for Hypertension-Cardiovascular Events.
The New England journal of medicine(2022)
摘要
In this large pragmatic trial of thiazide diuretics at doses commonly used in clinical practice, patients who received chlorthalidone did not have a lower occurrence of major cardiovascular outcome events or non-cancer-related deaths than patients who received hydrochlorothiazide. (Funded by the Veterans Affairs Cooperative Studies Program; ClinicalTrials.gov number, NCT02185417.).
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关键词
hydrochlorothiazide,hypertension–cardiovascular
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