Urine Leucine-Rich α-2 Glycoprotein 1 (LRG1) Predicts the Risk of Progression to End-Stage Kidney Disease in Patients With Type 2 Diabetes.

Jian-Jun Liu,Sylvia Liu,Jiexun Wang,Sharon L T Pek,Janus Lee,Resham L Gurung,Keven Ang,Yi Ming Shao,Subramaniam Tavintharan,Wern Ee Tang,Chee Fang Sum,Su Chi Lim

Diabetes care（2022）

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摘要

Urine LRG1, a TGF-β signaling modulator, predicts risk of progression to ESKD independently of clinical risk factors in patients with type 2 diabetes, suggesting that it may be a novel factor involved in the pathophysiological pathway leading to kidney disease progression.

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