Autoimmune reaction against pancreatic beta cells in children and adolescents with simple obesity.
Frontiers in endocrinology(2022)
摘要
Children and adolescents with simple obesity presented a higher prevalence of markers of autoimmune response against pancreatic beta cells than the general population. Most often, they had only one type of antibody - ICA. The presence of autoimmune response indicators against pancreatic islet antigens is more common in obese patients with impaired carbohydrate metabolism and is associated with lower insulin sensitivity.
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关键词
adolescents,anti-islet autoantibodies,children,diabetes,obesity
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