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Collagen is More Abundant and Structurally Altered in Lichen Sclerosus.

Urology(2023)

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摘要
LS tissues have greater collagen content compared to non-LS tissues. Quantitative assessment of collagen organization, using GLCM, revealed less homogeneity and more disorganization of collagen in LS compared to non-LS tissues. Taken together, our findings suggest that alterations in physical tissue properties seen in LS may be due to both increased collagen abundance and altered structure.
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关键词
Lichen sclerosus,extracellular matrix,fibrosis,urethral stricture
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