FcγRIIB inhibits inflammation in a murine model of psoriasis.

Irisu Nakabori,Yasuhito Hamaguchi,Kaori Sawada,Motoki Horii,Natsumi Fushida,Tasuku Kitano,Wang Chenyang,Jia Xibei,Yuichi Ikawa,Akito Komuro,Takashi Matsushita

Journal of dermatological science（2022）

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摘要

These results indicate that FcγRIIB likely plays a suppressive role in IMQ-induced, psoriasis-like skin inflammation. Furthermore, signal modulation via FcγRIIB is a potential therapeutic target for psoriasis.

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关键词

Cytokine,FcγRIIB,Imiquimod,Psoriasis-like skin inflammation

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