Antenna-enhanced mid-infrared detection of extracellular vesicles derived from human cancer cell cultures.

Maria Eleonora Temperini,Flavio Di Giacinto,Sabrina Romanò,Riccardo Di Santo,Alberto Augello,Raffaella Polito,Leonetta Baldassarre,Valeria Giliberti,Massimiliano Papi,Umberto Basile,Benedetta Niccolini,Ewa K Krasnowska,Annalucia Serafino,Marco De Spirito,Alessandra Di Gaspare,Michele Ortolani,Gabriele Ciasca

Journal of nanobiotechnology（2022）

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摘要

Thanks to the high protein sensitivity and the possibility to work with small sample volumes-two key features for ultrasensitive detection of extracellular vesicles- our lab-on-chip can positively impact the development of novel laboratory medicine methods for the molecular characterization of EVs.

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关键词

Biosensors,Extracellular Vesicles,IR spectroscopy,Nanomaterials,Plasmonics,SEIRA

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