Predicting the best fit based on the synergistic interaction of remifentanil and propofol at the corrected dose in elderly patients undergoing painless gastroscopy.

Jin-Feng Wang,Hai-Jun Xu, Xue-Mei He, Gang Tang,Li-Wei Wang, Wei Cheng

American journal of translational research(2022)

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Abstract
Remifentanil or propofol alone could not inhibit the somatic motor response at weight-adjusted doses among elderly patients. A combination of remifentanil and propofol showed a synergistic interaction in suppressing the motor response and adverse reactions in elderly patients. Preinjection of remifentanil could reduce the needed dose of propofol.
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Key words
Elderly patients,adverse reactions,corrected body weight,painless gastroscopy,propofol,remifentanil,somatic motor response
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