Association Between Autoimmune Rheumatic Diseases and Head and Neck Cancer: Systematic Review and Meta-Analysis.

Nancy Vanessa Rodrigues Batista,Remberto Marcelo Argandoña Valdez, Elma Mariana Verçosa de Melo Silva,Thayanara Silva Melo,José Ricardo Dias Pereira,Saman Warnakulasuriya,Alan Roger Santos-Silva,Angela Luzia Branco Pinto Duarte,Henrique de Ataíde Mariz,Luiz Alcino Gueiros

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology（2022）

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Abstract

Our study suggests that patients with autoimmune rheumatic diseases had a significantly increased risk of head and neck cancer compared with the general population, including thyroid, oral and nasopharyngeal cancers. These findings have implications for the individualized screening of these patients and the planning of specialist cancer services. The protocol is registered with PROSPERO, number CRD42020197827.

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Key words

Autoimmune Diseases,Head and neck Neoplasms,Meta-analysis,Rheumatic diseases,Systematic review

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