Donepezil alone and combined with intensive language-action therapy on depression and apathy in chronic post-stroke aphasia: A feasibility study

Marcelo L Berthier,Lisa Edelkraut,Francisco J López-González,Diana López-Barroso,Bettina Mohr,Friedemann Pulvermüller,Sergio E Starkstein,Ricardo E Jorge,María José Torres-Prioris,Guadalupe Dávila

Brain and Language（2023）

引用 4|浏览20

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摘要

•Depression and apathy are frequent aftermaths of post-stroke aphasia.•Depletion of acetylcholine can be leveraged with pharmacotherapy.•Cholinergic agent Donepezil combined with aphasia therapy improves mood disorders.

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关键词

Aphasia,Apathy,Depression,Donepezil,Intensive language-action therapy,Neuromaging,Pharmacotherapy,Stroke

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