Long term pregnancy outcomes of women with cancer following fertility preservation: A systematic review and meta-analysis

Zilin Xu, Sameh Ibrahim,Sarah Burdett,Larysa Rydzewska,Bassel H. Al Wattar, Melanie C Davies

European Journal of Obstetrics & Gynecology and Reproductive Biology(2022)

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摘要
•Only 8% of women returned to use their frozen reproductive material (558/7037, 8.0%), resulting in 210 live births in total, including assisted conceptions following EC/OC/OTC and natural conceptions following OTC.•The cumulative live birth rate following any fertility preservation treatment was 0.046 (95 %CI 0.029–0.066).•The overall LBR was highest in women who had EC (OR 0.45, 95 %CI 0.14–0.76), followed by OTC group (OR 0.37, 95 %CI 0.22–0.53) and OC group (OR 0.31, 95 %CI 0.15–0.47).•There was limited reporting on other important reproductive outcomes in this cohort including miscarriages, ectopic pregnancies and Caesarean sections rate.
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关键词
Fertility preservation,Embryo cryopreservation,Oocyte cryopreservation,Ovarian tissue cryopreservation,Cancer,Systematic review
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