Z-scores of bone turnover markers calculated from new established sex- and age-specific reference curves are associated to future change in BMD in children and adolescents

Bone(2022)

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摘要
•Bone turnover marker concentration varies widely with sex and age•Bone turnover markers peak two years earlier in girls compared to boys•(Pre)pubertal bone turnover is associated to change in bone mineral density
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关键词
Bone turnover markers,Reference curves,Children,Adolescents,Bone mineral density,Longitudinal analysis
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