Impact of latency-reversing agents on human macrophage physiology.
Immunity, inflammation and disease（2023）
Abstract
Our study reveals that LRAs can diversely impact basic physiologic features of human primary macrophages and could potentially decrease reactivation of nearby CD4 T cells latently infected with HIV-1. Our observations further stress the need to include different cell populations when assessing HIV-1 cure strategies.
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Key words
human animals,immunodeficiency diseases,monocytes/macrophages cells,viral/retroviral infections
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