Proteomic profiling of serum identifies a molecular signature that correlates with clinical outcomes in COPD.

Rania Dagher, Paul Fogel,Jingya Wang,David Soussan,Chia-Chien Chiang,Jennifer Kearley,Daniel Muthas,Camille Taillé,Patrick Berger,Arnaud Bourdin,Cécile Chenivesse,Sylvie Leroy,Gary Anderson,Alison A Humbles,Michel Aubier,Roland Kolbeck,Marina Pretolani

PloS one（2022）

引用 1|浏览16

暂无评分

摘要

This study provides insights into COPD heterogeneity and suggests that overexpression of factors involved in lung immunity/host defense, cell fate/repair/ remodelling and mitochondrial/metabolic activities contribute to better clinical outcomes. Hence, high throughput proteomic assay offers a powerful tool for identifying COPD endotypes and facilitating targeted therapies.

查看译文

关键词

proteomic profiling,copd,molecular signature,serum,clinical outcomes

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要