Association of CRISPR-Cas System with the Antibiotic Resistance and Virulence Genes in Nosocomial Isolates of Enterococcus .
Infection and drug resistance（2022）
Abstract
In conclusion, the results indicated that the absence of the CRISPR-Cas system was negatively associated with some antibiotic resistance in clinical isolates of and . Also, there was a negative correlation with the carriage of antibiotic resistance genes. Furthermore, CRISPR-Cas may prevent some isolates from acquiring certain virulence factors.
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Key words
CRISPR-Cas system,Enterococcus,antimicrobial-antibiotic resistance gene,virulence genes
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