Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve.

Luca Kleineidam,Steffen Wolfsgruber,Anne-Sophie Weyrauch,Linn E Zulka,Simon Forstmeier,Sandra Roeske,Hendrik van den Bussche,Hanna Kaduszkiewicz,Birgitt Wiese,Siegfried Weyerer,Jochen Werle,Angela Fuchs,Michael Pentzek,Christian Brettschneider,Hans-Helmut König,Dagmar Weeg,Horst Bickel,Melanie Luppa,Francisca S Rodriguez,Silka Dawn Freiesleben, Selin Erdogan, Chantal Unterfeld,Oliver Peters,Eike J Spruth,Slawek Altenstein,Andrea Lohse,Josef Priller,Klaus Fliessbach,Xenia Kobeleva,Anja Schneider,Claudia Bartels,Björn H Schott,Jens Wiltfang,Franziska Maier,Wenzel Glanz,Enise I Incesoy,Michaela Butryn,Emrah Düzel,Katharina Buerger,Daniel Janowitz,Michael Ewers,Boris-Stephan Rauchmann,Robert Perneczky,Ingo Kilimann,Doreen Görß,Stefan Teipel,Christoph Laske,Matthias H J Munk,Annika Spottke,Nina Roy,Frederic Brosseron,Michael T Heneka,Alfredo Ramirez,Renat Yakupov,Martin Scherer,Wolfgang Maier,Frank Jessen,Steffi G Riedel-Heller,Michael Wagner

Frontiers in psychology（2022）

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摘要

Our results support the link between OCR and CR. Promoting and seeking complex and stimulating work conditions in midlife could therefore contribute to increased resistance to pathologies in old age and might complement prevention measures aimed at reducing pathology.

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关键词

Alzheimer's disease,brain maintenance,brain reserve,cognitive reserve,mid-life cognitive demands,occupation

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