The Influence of Cannabidiol on the Pharmacokinetics of Methylphenidate in Healthy Subjects.

John S Markowitz,Ludmila De Faria,Qingchen Zhang,Philip W Melchert,Reginald F Frye,Brandon O Klee,Yuli Qian

Medical cannabis and cannabinoids（2022）

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摘要

Although the upper bound of bioequivalence was not met, the mean estimates of AUC and C ratios were generally small and unlikely to be of clinical significance.

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关键词

Cannabidiol,Cannabis,Carboxylesterase,Carboxylesterase 1,Drug interaction,Methylphenidate

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