Whole-exome rare-variant analysis of Alzheimer's disease and related biomarker traits.

Alzheimer's & dementia : the journal of the Alzheimer's Association(2022)

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摘要
The identification of these novel gene-trait associations offers new perspectives into the role of rare coding variation in the distinct pathophysiological processes culminating in AD, which may lead to identification of novel therapeutic and diagnostic targets.
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关键词
Alzheimer's disease,biomarkers,endophenotypes,rare coding variants,whole-exome sequencing
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