Engineering of gold nanorods as multifunctional theranostic agent for photothermal-enhanced radiotherapy of cancer

Lina Xie,Xia Ying,Xinyue Li,Xinyue Tan,Tianzi Zhang,Xujia Zhang,Wen Cai,Feifei An,Xiaoli Liu,Suxia Han

Materials & Design（2022）

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摘要

•The engineered GNRs-mediated PTT-RT demonstrated excellent photothermal-enhanced RT effect in two different pathological types of cell lines of cervical cancer.•The engineered GNRs exhibited capabilities of multi-modal imaging and PTT-RT.•The metabolomics analysis enriched the mechanism study for GNRs-mediated photothermal-enhanced RT.

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关键词

Gold nanorods (GNRs),Photothermal therapy (PTT),Radiotherapy (RT),Multi-modal imaging,Aggregation-induced emission (AIE)

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