Role of Neurite Outgrowth Inhibitor B Receptor in hepatic steatosis.

Hepatic steatosis, characterized by excessive lipid accumulation, is one of the common liver diseases. Neurite Outgrowth Inhibitor B Receptor (NgBR) regulates the lipid metabolism, cholesterol efflux, and protein glycosylation. Recently, it has been demonstrated that NgBR deficiency leads to hepatic steatosis. In this review we summarize the current knowledge about the structure of NgBR, the role and molecular mechanism of NgBR in the occurrence and development of hepatic steatosis.