Sleep benefit in patients with Parkinson’s disease is associated with the dopamine transporter expression in putamen

Rui-Fang Wang, Yan-Peng Li, Han-Yue Zhang,Sha-Sha Xu, Zhuo Wang,Xing-Min Han,Bao-Ping Liu

Brain Research(2023)

引用 1|浏览7
暂无评分
摘要
•The sleep benefit (SB) phenomenon was identified in PD patients and associated with sleep quality in PD patients.•SB variable was associated with the putamen 11C-CFT uptake index after correction for important clinical confounders. This provides evidence that SB phenomenon might be associated with dopamine terminal function and intracellular dopamine storage capacity in PD patients.•The putamen 11C-CFT uptake index has high capacity in predicting the SB in PD patients, and it is meaningful in discerning those PD patients with SB phenomenon who might be alleviated by improving the sleep quality instead of increasing the medication dose.
更多
查看译文
关键词
Sleep benefit,Dopamine transporter,Parkinson’s disease
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要